International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064

Research Paper | Histopathology | India | Volume 8 Issue 1, January 2019

Clinicopathological Prognostic Parameters in Oral Squamous Cell Carcinoma

Aarti Bansal, Narayanan Subramanian Mani

Aim: To determine the prognostic parameters in oral squamous cell carcinoma (OSCC). Methods: All cases were retrospectively and prospectively analyzed from August 2014 to July 2018 for various prognostic parameters. The parameters were divided into demographic, clinical and pathological groups. TNM pathological stage was determined in each case. Results: 53 cases were included. Male to female ratio was 1.3:1. Mean age was 58.9 years. Males reported greater risk prone habits to oral cancer than females. Tobacco usage was the predominant habit, with maximum number of cases showing duration of 20- 30 years of that habit. Medium socioeconomic and primary educational status was the commonest. Maximum number of patients presented within 6 months of onset of symptoms. Buccal mucosa and lower gingiva i.e. gingivobuccal sulcus was the most common affected site. Majority of patients presented in Stage III (49.1%). Staging by the current AJCC TNM system was done. Tumor size of >2 and 10 mm was the commonest. Moderately differentiated OSCC (45.3%) was predominant histological grade. 6 cases came out to be OSCC variants. Close surgical margins, PNI and LVI were identified more commonly in advanced stages. 40% cases had lymph node metastasis and 20% had extranodal extension. Conclusions: TNM classification had significant correlation with clinical and histopathological parameters. These highly significant results indicated that histologically invasive areas may be primarily responsible for clinical behaviour of the tumor and this may be important for therapy of choice for OSCC. The current AJCC TNM system of staging appears to be a better mechanism for assessment of tumor volume and predict the prognosis of OSCC. Analysis of the TNM system has been adopted to plan treatment and provide better evaluation of patient's evolution.

Keywords: Oral cancer, Oral squamous cell carcinoma, clinicopathological, prognosis

Edition: Volume 8 Issue 1, January 2019

Pages: 1283 - 1286


How to Cite this Article?

Aarti Bansal, Narayanan Subramanian Mani, "Clinicopathological Prognostic Parameters in Oral Squamous Cell Carcinoma", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20194513, Volume 8 Issue 1, January 2019, 1283 - 1286

48 PDF Views | 26 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'clinicopathological'

Research Paper, Histopathology, Iraq, Volume 6 Issue 8, August 2017

Pages: 478 - 483

Immunohistochemical Detection of BRAF in Iraqi Women with Different Breast Tumors

Ban Jasim Mohamad, Reyadh Salim Mohammed, Sajed Saad Mohammed, Faeza AftanZghair, Haneen Husam Mahmoud, Maryem Faris Hameed

Share this article

Research Paper, Histopathology, India, Volume 8 Issue 1, January 2019

Pages: 1283 - 1286

Clinicopathological Prognostic Parameters in Oral Squamous Cell Carcinoma

Aarti Bansal, Narayanan Subramanian Mani

Share this article

Similar Articles with Keyword 'prognosis'

Research Paper, Histopathology, Sudan, Volume 5 Issue 12, December 2016

Pages: 1829 - 1832

Immunohistochemical Expression of P53 in Colorectal Tumors among Sudanese Patients

Ahmed Hasan Ahmed Guzailan, Mohammed Siddig Abdal-Aziz, Ahmed Abde lbadie Mohammed, Mai Abdul Rahman Masri

Share this article

Case Studies, Histopathology, India, Volume 5 Issue 10, October 2016

Pages: 200 - 203

Ovarian Sertoli-Leydig Cell Tumour, A Rare Neoplasm: A Case Report

Dr. Sujata S Giriyan, Dr. Sameera N

Share this article

Research Paper, Histopathology, India, Volume 6 Issue 3, March 2017

Pages: 1293 - 1297

AgNOR study in Colorectal Carcinoma with Correlation of Histopathological Grade and UICC Stage

Saravanan B, Surekha M R, Ashok S

Share this article

Research Paper, Histopathology, India, Volume 8 Issue 1, January 2019

Pages: 1283 - 1286

Clinicopathological Prognostic Parameters in Oral Squamous Cell Carcinoma

Aarti Bansal, Narayanan Subramanian Mani

Share this article

Research Paper, Histopathology, Indonesia, Volume 7 Issue 6, June 2018

Pages: 245 - 248

The Association between CD10 Expression and Histological Grade in Invasive Breast Carcinoma of No Special Type

I Gusti Ayu Ari Kusumawati, Luh Putu Iin Indrayani Maker, I Gusti Alit Artha

Share this article

Top