International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 173 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Chemistry | India | Volume 8 Issue 1, January 2019


Determination of Iron (III) and Iron (II) from Iron Sucrose Injection and Iron Polymaltose by Ion Chromatography

Dr. Chetan Chavan, Chanakya Thaker, Chetan Chaudhari


Abstract: An accurate, simple, reproducible, and sensitive method for the estimation of Iron (III) and Iron (II) was developed and validated. Iron (III) and Iron (II) weres separated using chelation ion chromatography technique using isocratic elution with a flow rate of 1.2mL/min. Post column derivatization with 4- (2-pyridylazo) resorcinol (PAR) was carried out to form light abosrbing complex an detected at 530nm. The mobile phase include pyridine-2, 6-dicarboxylate (PDCA) which acts as chelating agent and helps to retain Iron (III) and Iron (II) on mixed mode separator column. The linearlity of method has been tested in the range of 5.0mg/L to 15mg/L of Iron (III) and 0.5mg/L to 1.5mg/L of Iron (II) and correlation cofficient (R2) was >0.999 for both Iron (III) and Iron (II). The method was shown excellent reproducible, linear, specific, sensitivity, rugged. The Limits of Detection and Quantification have been also established for Iron (III) as 0.05mg/L & 0.1mg/L and for Iron (II) as 0.3mg/L & 0.5mg/L respectively. Hence, the validated method is easy to adapt for regular analysis.


Keywords: Iron Sucrose, Iron Polymaltose, Post Column Reagent, Iron Speciation, Ion Chromatography, Chelation, PDCA, PAR


Edition: Volume 8 Issue 1, January 2019,


Pages: 749 - 753


How to Cite this Article?

Dr. Chetan Chavan, Chanakya Thaker, Chetan Chaudhari, "Determination of Iron (III) and Iron (II) from Iron Sucrose Injection and Iron Polymaltose by Ion Chromatography", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20194191, Volume 8 Issue 1, January 2019, 749 - 753

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Ion Chromatography'

Downloads: 22

Research Paper, Chemistry, India, Volume 10 Issue 4, April 2021

Pages: 307 - 312

Quantification of Cyclophosphamide Impurities in Cyclophosphamide Drug Substance and formulations by Ion chromatography

Dr. Chetan Chavan, Chanakya Thaker, Chetan Chaudhari

Share this Article

Downloads: 30

Research Paper, Chemistry, India, Volume 10 Issue 4, April 2021

Pages: 223 - 226

Ion Chromatography Method Development and Validation for Assay of Sodium Thiosulfate

Chanakya Thaker, Dr. Chetan Chavan, Chetan Chaudhari

Share this Article

Similar Articles with Keyword 'Chelation'

Downloads: 5

Research Paper, Chemistry, Nigeria, Volume 10 Issue 8, August 2021

Pages: 949 - 961

Chemical Synthesis and Microbial Evaluation of Iron (II) and Cobalt (II) Complexes of Schiff Base Dervived from ?-Hydroxynapthalene-1-Carbaldehyde Using 2-Aminoaniline and 2-Hydroxyaniline as the Aniline Di-Substituents

Ezenweke Linus Obi, Ojiako Eugenia Nonye, Esonwune Anacletus Anayochukwu, Olugbue Victor U.

Share this Article

Downloads: 112

Research Paper, Chemistry, Iraq, Volume 6 Issue 8, August 2017

Pages: 2211 - 2214

Spectrophotometric and Thermodynamic Studies of Complexation between Catechin and Some of Transition Metals (II)

Ahmed.N Abd, Elham.M Al-Rufaie, Haider.N Hussein

Share this Article

Similar Articles with Keyword 'PAR'

Downloads: 127

Research Paper, Chemistry, India, Volume 5 Issue 5, May 2016

Pages: 2066 - 2070

Comparative Study of the Antiurolithiatic Activity of Plant Hydroalcoholic Extract of Argemone mexicana, Cissus javana DC and Garcinia pendunculata

O. Ibopishak Singh, A. Bimola Devi

Share this Article

Downloads: 117 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Review Papers, Chemistry, United Kingdom, Volume 4 Issue 12, December 2015

Pages: 2133 - 2135

African Shea Butter as a Staple and Renewable Bioproduct

Kaana Asemave, Tabitha Amarkasev Asemave

Share this Article

Similar Articles with Keyword 'Iron'

Downloads: 53

Research Paper, Chemistry, Nigeria, Volume 2 Issue 3, March 2013

Pages: 457 - 459

Selenium Content in some Brands of Bottled Beer Marketed in Makurdi Town Benue State, Nigeria

A. D. Oklo, R. Sha'Ato, K. Asemave, C.Mkurzurum

Share this Article

Downloads: 117 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Review Papers, Chemistry, United Kingdom, Volume 4 Issue 12, December 2015

Pages: 2133 - 2135

African Shea Butter as a Staple and Renewable Bioproduct

Kaana Asemave, Tabitha Amarkasev Asemave

Share this Article

Similar Articles with Keyword 'Post'

Downloads: 82

Research Paper, Chemistry, Nigeria, Volume 2 Issue 6, June 2013

Pages: 393 - 395

Trends In Students Achievement In Senior School Certificate Examination (SSCE) In Chemistry Between 2008 And 2012

Adamu Ademola. S, Boris Olufunke.O, Kenni Amoke. M

Share this Article

Downloads: 89

Research Paper, Chemistry, Nigeria, Volume 9 Issue 12, December 2020

Pages: 189 - 194

Chemical Analysis of Improvised Limestone Ore Concentrate: A Resource for Teaching the Concept of Qualitative Analysis in Practical Chemistry

Ugbe Agioliwhuugbe, Charles Igiri Egonyi

Share this Article

Similar Articles with Keyword 'Column'

Downloads: 1

Research Paper, Chemistry, Sudan, Volume 10 Issue 5, May 2021

Pages: 444 - 448

Isolation and Structural Elucidation of three Substituted Flavones from Croton Zambesicus (Mull) Fruit and Leaves

Mustafa S.Koya, Nada A. Elamin, Zeinab A. Elrabei

Share this Article

Downloads: 22

Research Paper, Chemistry, India, Volume 10 Issue 4, April 2021

Pages: 307 - 312

Quantification of Cyclophosphamide Impurities in Cyclophosphamide Drug Substance and formulations by Ion chromatography

Dr. Chetan Chavan, Chanakya Thaker, Chetan Chaudhari

Share this Article

Similar Articles with Keyword 'Reagent'

Downloads: 153

Research Paper, Chemistry, Iraq, Volume 7 Issue 8, August 2018

Pages: 39 - 43

p-Aminobenzoic Acid as a New Reagent in Spectrophotometric Determination of Salbutamol Sulphate Via Oxidative Coupling Reaction

Nabeel S. Othman Ali M. Asaad

Share this Article

Downloads: 1

Comparative Studies, Chemistry, Niger, Volume 10 Issue 6, June 2021

Pages: 1415 - 1417

Comparative Study of the Quality Control of Metronidazole Sold in Niamey City by Thin Layer Chromatography (TLC)

Salifou Karimoune FADJIMATA, Amadou Tidjani ILAGOUMA

Share this Article

Similar Articles with Keyword 'Speciation'

Downloads: 101

Research Paper, Chemistry, India, Volume 4 Issue 11, November 2015

Pages: 1307 - 1310

Speciation of Binary Complexes of Pb(II), Cd(II) and Hg(II) with L-Valine in Low Dielectric Media

Dr. P. Bhushanavathi, Dr. P. Sarada

Share this Article

Downloads: 106

Research Paper, Chemistry, India, Volume 4 Issue 2, February 2015

Pages: 1351 - 1358

Speciation Studies of Dimethyltin (IV) and Trimethyltin (IV) - Carboxylates Systems

Meena Devi, Renu Nair Ahuja

Share this Article

Similar Articles with Keyword 'Ion'

Downloads: 53

Research Paper, Chemistry, Nigeria, Volume 2 Issue 3, March 2013

Pages: 457 - 459

Selenium Content in some Brands of Bottled Beer Marketed in Makurdi Town Benue State, Nigeria

A. D. Oklo, R. Sha'Ato, K. Asemave, C.Mkurzurum

Share this Article

Downloads: 127

Research Paper, Chemistry, India, Volume 5 Issue 5, May 2016

Pages: 2066 - 2070

Comparative Study of the Antiurolithiatic Activity of Plant Hydroalcoholic Extract of Argemone mexicana, Cissus javana DC and Garcinia pendunculata

O. Ibopishak Singh, A. Bimola Devi

Share this Article

Similar Articles with Keyword 'Chromatography'

Downloads: 1

Research Paper, Chemistry, Sudan, Volume 10 Issue 5, May 2021

Pages: 444 - 448

Isolation and Structural Elucidation of three Substituted Flavones from Croton Zambesicus (Mull) Fruit and Leaves

Mustafa S.Koya, Nada A. Elamin, Zeinab A. Elrabei

Share this Article

Downloads: 1

Comparative Studies, Chemistry, Niger, Volume 10 Issue 6, June 2021

Pages: 1415 - 1417

Comparative Study of the Quality Control of Metronidazole Sold in Niamey City by Thin Layer Chromatography (TLC)

Salifou Karimoune FADJIMATA, Amadou Tidjani ILAGOUMA

Share this Article
Top