Comparative Studies | Medical Sciences | India | Volume 8 Issue 3, March 2019
Comparison of Two Different Doses of Dexmedetomidine in Decreasing the Extubation Response
Roshni Sebastian, Harshavardhan K
BACKGROUND: Laryngoscopy, intubation and extubation is associated with sympathetic stimulation which results in hypertension and tachycardia. Drugs modulating the sympathetic response can be used during extubation to decrease the sympathetic response AIM: To compare of two different doses of dexmedetomidine in decreasing the sympathetic response.. METHOD: A hospital based Prospective, randomized, double blind study where a total of 66 patients undergoing surgery under general Anaesthesia in our hospital were randomly divided into 2 groups: Group-D1: Dexmedetomidine (0.25mcg/kg) group 33 patients; Group-D2: Dexmedetomidine (0.5mcg/kg) group 33 patients. The hemodynamic parameters, airway reflexes were assessed in different intervals of time and compared. RESULT: heart rate and systolic and diastolic blood pressure were significantly lower in D2 group (0.5 g/kg) as compared to D1 group (0.2 g/kg ).Smooth extubation was reported in 93.9 % cases of D2 group as compared to 81.8 % in D1 group. Rough experience was seen in 18.2 % cases of D1 group as compared to 6.1 % in D2 group (p-0.25). Mean time for extubation was significantly lower in D2 group (136.7 vs 224.5 sec; p
Keywords: extubation, dexmedetomidine, sympathetic response
Edition: Volume 8 Issue 3, March 2019
Pages: 380 - 383
How to Cite this Article?
Roshni Sebastian, Harshavardhan K, "Comparison of Two Different Doses of Dexmedetomidine in Decreasing the Extubation Response", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20193036, Volume 8 Issue 3, March 2019, 380 - 383
89 PDF Views | 48 PDF Downloads
Similar Articles with Keyword 'extubation'
Research Paper, Medical Sciences, India, Volume 9 Issue 1, January 2020
Pages: 963 - 967Comparison of Dexmedetomidine and Magnesium Sulphate in Attenuating Airway and Hemodynamic Response during Extubation in Patients Undergoing Craniotomies - A Randomised Clinical Trial
Dr Sivanayak Vudithe, Dr. Vindhya K
Research Paper, Medical Sciences, India, Volume 8 Issue 5, May 2019
Pages: 726 - 732A Study of Post Extubation Endotracheal Tube Microbial Colonisation in Patients Undergoing Elective Postoperative Mechanical Ventilation
Singla S, Kohli P, Pandey M
Comparative Studies, Medical Sciences, India, Volume 8 Issue 3, March 2019
Pages: 1413 - 1414Effect of Ketamine Nebulization in Reduction of Incidence and Severity of Post?Operative Sore Throat-A Prospective Comparative Study
Dr. M. G. Rajinish Singhm.D, Dr. K. Ravindran, Dr. Edward Johnson, S. Kanthammal
Comparative Studies, Medical Sciences, India, Volume 8 Issue 3, March 2019
Pages: 380 - 383Comparison of Two Different Doses of Dexmedetomidine in Decreasing the Extubation Response
Roshni Sebastian, Harshavardhan K
Similar Articles with Keyword 'dexmedetomidine'
Case Studies, Medical Sciences, India, Volume 8 Issue 9, September 2019
Pages: 1314 - 1317Effects of Intravenous Dexmedetomidine Premedication on Hemodynamics Changes during Laparoscopic Cholecystectomy
Dr Sweta Gulati, Dr Srinivasa Murthy
Research Paper, Medical Sciences, India, Volume 8 Issue 12, December 2019
Pages: 984 - 987Epidural Labour Analgesia What?s New: Comparison of 0.125% Ropivacaine-Dexmedetomidine versus 0.125% Levobupivacaine-dexmedetomidine
Satinder Kaur, Meena Singh, Arin Choudhury, Pramod Kumar, Namita Misra, Manjit Kaur Mohi
Research Paper, Medical Sciences, India, Volume 9 Issue 1, January 2020
Pages: 1055 - 1060Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjunct to Thoracic Epidural in Patients Undergoing upper Abdominal Surgery: A Prospective Randomized Controlled Trial
Dr. K. Gopa Naik, Dr. A. Vishnu Vardhan
Research Paper, Medical Sciences, India, Volume 9 Issue 1, January 2020
Pages: 963 - 967Comparison of Dexmedetomidine and Magnesium Sulphate in Attenuating Airway and Hemodynamic Response during Extubation in Patients Undergoing Craniotomies - A Randomised Clinical Trial
Dr Sivanayak Vudithe, Dr. Vindhya K
Research Paper, Medical Sciences, India, Volume 8 Issue 5, May 2019
Pages: 635 - 638Evaluation of Efficacy of Intravenous Dexmedetomidinein Post-Operative Care of Cardiac Surgery Patients
Dr Sachin Shouche, Dr Satish Kumar Mishra, Dr Rangraj Setlur, Dr Shishir Kumar