A Comparative Study of Attenuation of Propofol Induced Pain by Lignocaine, Ondansetron, Dexamethasone and Cold Propofol per se.
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

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Research Paper | Medicine Science | India | Volume 7 Issue 2, February 2018

A Comparative Study of Attenuation of Propofol Induced Pain by Lignocaine, Ondansetron, Dexamethasone and Cold Propofol per se.

Mitesh Patel, Neepa Patel, Pragna Vachchrajani

Background Pain on injection of propofol is a common problem.Aim of this study was to compare the efficacy of lignocaine, ondansetrone, dexamethasone and cold propofol per se as a pretreatment drug for attenuation of pain due to propofol injection.Materials and Methods Fifty two ASA and patients were randomly assigned into four groups (13 in each).Group O received 0.1mg/kg ondansetron, Group L received 0.5mg/kg lignocaine, Group D received 0.1mg/kg dexamethasone, Group T received propofol 1 % at 4 2mg/kg. Mid forearm was occluded manually before injection of pre-treatment drug and released after 1 min and then propofol was injected over 5 sec. Patients were observed and questioned 15 sec later if they had pain and pain was assessed using four point scale0 = no pain, 1 = mild pain, 2 = moderate pain, 3 = severe pain.ResultThe incidence and intensity of pain were significantly less in all groups. We observed mild to moderate pain in Group L, O, D, and T were 31 %, 54 %, 46 % and 77 % respectively. The incidence of score 0 was significantly higher in Group L (70 %) and Group D (54 %) and Group O (46 %) than Group T (23 %) (p

Keywords: Propofol pain, lignocaine, dexamethasone, ondansetrone, cold propofol

Edition: Volume 7 Issue 2, February 2018

Pages: 603 - 606

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Mitesh Patel, Neepa Patel, Pragna Vachchrajani, "A Comparative Study of Attenuation of Propofol Induced Pain by Lignocaine, Ondansetron, Dexamethasone and Cold Propofol per se.", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART201837, Volume 7 Issue 2, February 2018, 603 - 606

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