Downloads: 160 | Views: 169
Research Paper | Medicine Science | India | Volume 7 Issue 2, February 2018
A Comparative Study of Attenuation of Propofol Induced Pain by Lignocaine, Ondansetron, Dexamethasone and Cold Propofol per se.
Mitesh Patel [3] | Neepa Patel | Pragna Vachchrajani
Abstract: Background Pain on injection of propofol is a common problem. Aim of this study was to compare the efficacy of lignocaine, ondansetrone, dexamethasone and cold propofol per se as a pretreatment drug for attenuation of pain due to propofol injection. Materials and Methods Fifty two ASA and patients were randomly assigned into four groups (13 in each). Group O received 0.1mg/kg ondansetron, Group L received 0.5mg/kg lignocaine, Group D received 0.1mg/kg dexamethasone, Group T received propofol 1 % at 4 2mg/kg. Mid forearm was occluded manually before injection of pre-treatment drug and released after 1 min and then propofol was injected over 5 sec. Patients were observed and questioned 15 sec later if they had pain and pain was assessed using four point scale0 = no pain, 1 = mild pain, 2 = moderate pain, 3 = severe pain. ResultThe incidence and intensity of pain were significantly less in all groups. We observed mild to moderate pain in Group L, O, D, and T were 31 %, 54 %, 46 % and 77 % respectively. The incidence of score 0 was significantly higher in Group L (70 %) and Group D (54 %) and Group O (46 %) than Group T (23 %) (p
Keywords: Propofol pain, lignocaine, dexamethasone, ondansetrone, cold propofol
Edition: Volume 7 Issue 2, February 2018,
Pages: 603 - 606
Similar Articles with Keyword 'lignocaine'
Downloads: 112
Research Paper, Medicine Science, India, Volume 5 Issue 1, January 2016
Pages: 1267 - 1271A Clinical Study to Compare the Efficacy of Pretreatment with Granisetron and Lignocaine to Alleviate Pain on Propofol Injection
B. P. Manjula [2] | Balachandra S. R.
Downloads: 130 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medicine Science, India, Volume 6 Issue 9, September 2017
Pages: 552 - 555Comparative Evaluation of Efficacy of Plain Xylocaine 0.5% (3mg/kg) with Xylocaine 0.5% (3mg/kg) + Buprenorphine (3?g/kg) in Intravenous Regional Anesthesia (Holme's Modification of Bier's Block)
Dr. N. Periyasamy | Prof. Dr. G. Sivakumar