International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064




Downloads: 135

Research Paper | Medicine Science | India | Volume 7 Issue 1, January 2018


A Comparative Evaluation of Dexmedetomidine and Clonidine as an Adjuvant to Ropivacaine in Epidural Anaesthesia for Intraoperative and Postoperative Sedation and Analgesia

Dr. Vijeta Khandelwal | Dr. Khushboo Malav | Dr. S.P. Chittora [2] | Dr. Gajanand Dhaked [2]


Abstract: Background - This prospective randomized double blind study was carried out to evaluate and compare the effect of dexmedetomidine and clonidine as an adjuvant to ropivacaine in epidural anaesthesia. Method - Ninety patients (ASA grade I and II), were randomly allocated into three groups of 30 patients in each. Group A (R) received 17 ml of 0.75 % ropivacaine + 2ml saline (control), group B (RD) received dexmedetomidine 1.5g/kg in 2ml+ 17 ml of 0.75 % ropivacaine and group C (RC) received clonidine 2g/kg in 2ml+17 ml of 0.75 % ropivacaine in epidural anaesthesia. All three groups were evaluated in terms of onset of analgesia, duration of analgesia, motor block, sedation and any untoward side effects. Results - Onset of analgesia (sensory block) was earlier in group B (8.132.02 mins) than group A (12.133.37 mins) and group C (9.862.84 mins) (p


Keywords: Dexmedetomidine, Clonidine, Ropivacaine, Alpha 2 agonist, Epidural anaesthesia


Edition: Volume 7 Issue 1, January 2018,


Pages: 1085 - 1090


How to Cite this Article?

Dr. Vijeta Khandelwal, Dr. Khushboo Malav, Dr. S.P. Chittora, Dr. Gajanand Dhaked, "A Comparative Evaluation of Dexmedetomidine and Clonidine as an Adjuvant to Ropivacaine in Epidural Anaesthesia for Intraoperative and Postoperative Sedation and Analgesia", International Journal of Science and Research (IJSR), Volume 7 Issue 1, January 2018, pp. 1085-1090, https://www.ijsr.net/get_abstract.php?paper_id=ART20179508

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