International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064




Downloads: 152

Research Paper | Medicine Science | India | Volume 6 Issue 2, February 2017


Diagnostic value of Line Probe Assay in Childhood Tuberculosis

Dr. Shehraz Firoz | Dr. Hayat Anjum Khan


Abstract: Objective- This study was conducted in children with tuberculosis (TB) to compare the diagnostic yield of Genotype LPA assay and its comparison with MGIT culture in various body fluids and also to detect drug resistance using LPA. Methods -Children < 18 years diagnosed as TB were included in the study. Body fluids obtained from these subjects were processed for LPA assay and MGIT culture and. Drug resistance was detected using LPA. Results - 80 TB cases were registered. LPA in showed a high sensitivity of 91.1 % and specificity of 75 %. High MDR TB (44 %) was detected using LPA. Conclusion- Genotype LPA can serve as a reliable tool of clinical utility for diagnosis of TB and detection of drug resistance.


Keywords: Tuberculosis, Genotype LPA, MGIT, MDR TB


Edition: Volume 6 Issue 2, February 2017,


Pages: 841 - 842


How to Cite this Article?

Dr. Shehraz Firoz, Dr. Hayat Anjum Khan, "Diagnostic value of Line Probe Assay in Childhood Tuberculosis", International Journal of Science and Research (IJSR), Volume 6 Issue 2, February 2017, pp. 841-842, https://www.ijsr.net/get_abstract.php?paper_id=ART2017833

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