International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064

Research Paper | Medicine Science | Iraq | Volume 6 Issue 11, November 2017

Incidence of Polyoma Virus Allograft Nephropathy among Iraqi Kidney Transplant Patients

Jawad Ibrahim Rasheed, Ali Abdulmajid Dyab Allawi, Safa Auldeen Jameel Alzuhairi

Background polyoma virus is a ubiquitous human virus with a peak incidence of primary infection in children 2 to 5 years of age and a seroprevalence rate of more than 60% to 90% among the adult population worldwide. Material and methodsAll recruited patients were considered from nephrology and transplant outpatients' clinic medical city (162cases, 97 males& 65 females). The patients with graft dysfunction were recorded on an already prepared data sheet for the type of induction therapy antithymocyte globulin (ATG or baxiliximab ), type of immunosuppressant regimens , renal function test by estimation of Glomerular filtration rate(GFR by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, renal Doppler ultrasound , urine for decoy cell and renal graft biopsy for light microscopy and immunohistochmestry stain. ResultsThis cohort study enrolled Male patients were 97 while female patients were 65, the age ranges from 20 to 60 years 1 .There was high incidence of PVAN among patients receiving antithymocyte globulin (ATG) (28.6%) as compare to baxiliximab group (3%). There were increasing incidence of BK virus nephropathy among patients taking (Calcineurin inhibitors (CNIs), + Steroid + Mycophenolate mofetil (MMF)), group (1) patients, the difference was statistically significant (p=0.012). There was increasing incidence of decoy cells in the urine of patients with PVAN (100%). ConclusionsThere was increasing incidence of PVAN among transplant recipient's patients. Histological feature of PVAN is reliable diagnostic tool and should be consider in every renal transplant patients.

Keywords: Graft Rejection, Kidney Transplantation, Polyomavirus

Edition: Volume 6 Issue 11, November 2017

Pages: 1539 - 1544


How to Cite this Article?

Jawad Ibrahim Rasheed, Ali Abdulmajid Dyab Allawi, Safa Auldeen Jameel Alzuhairi, "Incidence of Polyoma Virus Allograft Nephropathy among Iraqi Kidney Transplant Patients", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20178297, Volume 6 Issue 11, November 2017, 1539 - 1544

2 PDF Views | 3 PDF Downloads

Download Article PDF

Video Lecture of Above Article is Not Available Yet

You be the First to Request! Press the Button below!



Similar Articles with Keyword 'Graft Rejection'

Research Paper, Medicine Science, Iraq, Volume 6 Issue 11, November 2017

Pages: 1539 - 1544

Incidence of Polyoma Virus Allograft Nephropathy among Iraqi Kidney Transplant Patients

Jawad Ibrahim Rasheed, Ali Abdulmajid Dyab Allawi, Safa Auldeen Jameel Alzuhairi

Share this article

Research Paper, Medicine Science, India, Volume 7 Issue 4, April 2018

Pages: 621 - 624

Surgical Outcomes of Non Descemet?s Stripping Endothelial Keratoplasty: Analysis of 100 Consecutive Cases

Dharamveer Singh Choudhary, Nikhil Agrawal, Nikita Sharma

Share this article

Top