International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Medicine Science | India | Volume 6 Issue 8, August 2017

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

DOTS strategy, as recommended by the WHO after declaring tuberculosis as a global emergency in 1993, is a very important landmark in the history of tuberculosis control. Supervised, intermittent chemotherapy was found to be operationally impracticable under National Tuberculosis Control Program. Hence Cost effective strategy directly observed intermittent chemotherapy for tuberculosis control under RNTCP has been formulated and implemented. It has long been proved to be effective in various trials in India. Under DOTS strategy, the main emphasis is on diagnosing and treating sputum smear positive patients, thus the stress on sputum microscopy. The patients are categorized into two categories according to status of the disease and previous treatment history. Various published reports indicate a very high efficacy of treatment regimens with cure rates of 80-100 % under RNTCP. However follow up reports of relapse rate on patients who have completed treatment under RNTCP are very few. Relapse rate, an important indicator of success of any treatment regimen, has not been measured under program condition. Follow up study of 203 patients was done to examine the rate of relapse among sputum smear positive pulmonary tuberculosis patients who have successfully completed treatment and declared either cured or treatment completed. Majority of 21/32 (65.6 %) relapses were occurred in those who gained less than 4 kg weight gain during treatment. Further the maximum number 64 % (16/25) among Category-1 patients and 71.43 % (5/7) among Category-II patients relapsed within first 6 month of follow up period.

Keywords: Tuberculosis, RNTCP, DOTS, Cured, Relapse, Category-I, Category-II, Weight Gain

Edition: Volume 6 Issue 8, August 2017

Pages: 1896 - 1903


How to Cite this Article?

Dr. Vinay Mohan, Dr. Sunita Devi, "Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20176491, Volume 6 Issue 8, August 2017, 1896 - 1903

23 PDF Views | 25 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Tuberculosis'

Research Paper, Medicine Science, India, Volume 3 Issue 6, June 2014

Pages: 1591 - 1598

Increasing Prevalence of Chronic Obstructive Pulmonary Disease;Tuberculosis; Lung Cancer and Rising Environmental Oestrogen

Elizabeth JeyaVardhini Samuel, Nagarajan Natarajan

Share this article

Research Paper, Medicine Science, Saudi Arabia, Volume 3 Issue 7, July 2014

Pages: 1402 - 1406

Diagnostic Utility of ZN, IH and PCR in Detection of Tuberculous Lymphadenopathy: A Retrospective Study from Sudan

Ihab Hamed Nourein, Hussain Gadelkarim Ahmed, Abuobieda Balla Abusharib, Maysa Badawi Elmubasher, Sara Abul Gasim Seif el din. Fawaz Alshammari

Share this article

Research Paper, Medicine Science, India, Volume 4 Issue 10, October 2015

Pages: 1498 - 1500

Role of Fiberoptic Bronchoscopy in Establishing the Diagnosis of Various Lung Diseases in a Tertiary Care Hospital

Dr Abhinav Sharma, Dr Nikita Gandotra

Share this article

Research Paper, Medicine Science, India, Volume 5 Issue 2, February 2016

Pages: 1714 - 1719

A Retrospective Study of Probable Risk Factors for Default on Dots for Tuberculosis at a Tertiary Care Hospital in Western Maharashtra

Dr. Anita Saibannavar, Dr. Sanjay Desai

Share this article

Research Paper, Medicine Science, Indonesia, Volume 4 Issue 6, June 2015

Pages: 2950 - 2952

Hyperglicemia IncreasedThe Expression of TLR2 mRNA and Coronin-1A Level in Lung Mice which were infected by Mycobacterium Tuberculosis

Wande IN, Sutirta Yasa IWP, Linawati NM

Share this article



Similar Articles with Keyword 'RNTCP'

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 1896 - 1903

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

Share this article

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 992 - 994

Preliminary Report of Forty Three XDR TB Cases Admitted in DR-TB Center in GMCH, Aurangabad

Mangala Sonavani Borkar, Avinash Lamb, Gajanan Surwade, Rohit Walse, Pranay Jambhulkar, Amol Karde

Share this article



Similar Articles with Keyword 'DOTS'

Research Paper, Medicine Science, India, Volume 5 Issue 2, February 2016

Pages: 1714 - 1719

A Retrospective Study of Probable Risk Factors for Default on Dots for Tuberculosis at a Tertiary Care Hospital in Western Maharashtra

Dr. Anita Saibannavar, Dr. Sanjay Desai

Share this article

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 1896 - 1903

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

Share this article

Case Studies, Medicine Science, India, Volume 2 Issue 5, May 2013

Pages: 334 - 337

Unusual Presentation Of Tuberculosis In Head & Neck Region

Aakanksha Rathor, Smrity Dutta

Share this article

M.Tech / M.E / PhD Thesis, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 618 - 622

Alcohol and Tobacco Use among the HIV/TB Co-Infected Individuals: A Case of Nepal

Bhim Bahadur Subba 'Phudong'; Dr. Nirmal Rimal

Share this article

Research Paper, Medicine Science, India, Volume 5 Issue 5, May 2016

Pages: 817 - 820

A Study to Identify the Factors Influencing Quality of Life in Patients With Pulmonary Tuberculosis and to Develop A Self Instructional Module to Enhance the Quality of Life of Patients with Pulmonary Tuberculosis in Selected Dots Centres of Delhi

Shabana Khatun

Share this article



Similar Articles with Keyword 'Cured'

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 1896 - 1903

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

Share this article

Case Studies, Medicine Science, Turkey, Volume 4 Issue 3, March 2015

Pages: 514 - 515

An Interesting Way of Thinner Abuse: A Case Report

Yeliz Simsek, Esra Mercanoglu Efe

Share this article

Review Papers, Medicine Science, India, Volume 7 Issue 4, April 2018

Pages: 1362 - 1364

Review about the Signs of Commencing Improvement after Administration of Homoeopathic Medicine

Dr. Shweta Patil

Share this article

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 992 - 994

Preliminary Report of Forty Three XDR TB Cases Admitted in DR-TB Center in GMCH, Aurangabad

Mangala Sonavani Borkar, Avinash Lamb, Gajanan Surwade, Rohit Walse, Pranay Jambhulkar, Amol Karde

Share this article

Research Paper, Medicine Science, Egypt, Volume 5 Issue 2, February 2016

Pages: 656 - 662

Evaluation of a Newly Formulated Thermoplastic Monomer Free Complete Denture Base Material (Microbiological Study)

Ahmed Abdelhamid, Medhat Ashour, Abdelrahman Mohamed Abdelrahman

Share this article



Similar Articles with Keyword 'Relapse'

Research Paper, Medicine Science, Egypt, Volume 6 Issue 5, May 2017

Pages: 1187 - 1192

Amino Acid Substitution in Hepatitis C Virus Core and Genetic Variation in Interleukin 28? Gene and their Correlation to Interferon Treatment Failure in Chronic HCV Egyptian Patients

Nashwa El-Khazragy, Maiada A. Hussien, Mohamed A. El-Mordy, Amany M. Maher

Share this article

Dissertation Chapters, Medicine Science, India, Volume 3 Issue 12, December 2014

Pages: 1078 - 1082

A Comparison between Intracavitary Brachytherapy and Interstitial Brachytherapy in Carcinoma Cervix (Stage IIB and Stage IIIB) - Prospective Randomized Study

Sridhar.P, Thejaswini.B, Giri.G.V, Nanda.R

Share this article

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 1896 - 1903

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

Share this article

Research Paper, Medicine Science, India, Volume 5 Issue 1, January 2016

Pages: 1600 - 1602

An Exploratory Study to Identify the Risk Factors for Relapse in Patients with Alcohol Dependence following Abstinence in Selected Drug de Addiction and Rehabilitation Centers of New Delhi, India

Binu Thomas, Bindu Shaiju, Veena Sharma

Share this article

Research Paper, Medicine Science, India, Volume 8 Issue 10, October 2019

Pages: 755 - 761

Ocular Manifestations in Rheumatoid Arthritis and their Co-Relation with Anti Cyclic Citrullinated Peptide Antibodies

Dr. Indira Pegu, Dr. Bharoti S. Puzari, Dr. Sanjeeb Kakati, Dr. Gargi Choudhury

Share this article



Similar Articles with Keyword 'Weight Gain'

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 1896 - 1903

Initial Higher Sputum Graded Patients Treated Under Category-II RNTCP (DOTS) with Low Weight Gain Tend to Have More Relapse Rate

Dr. Vinay Mohan, Dr. Sunita Devi

Share this article

Research Paper, Medicine Science, Iraq, Volume 5 Issue 1, January 2016

Pages: 1603 - 1603

Low Birth Weight and Exposure to Violence in Iraq

Wasan Ismail Ibrahim, Aliaa Makki Hassan, Eman Adnan Al-Kaseer

Share this article

Research Paper, Medicine Science, India, Volume 3 Issue 2, February 2014

Pages: 203 - 210

Epidemiological Correlates of Use of Contraceptives Methods and Appraisal of Health Education on Status of Knowledge and Practices among Married Woman

Shabana Anjum, P.M. Durgawale, Mahadeo Shinde

Share this article

Research Paper, Medicine Science, India, Volume 3 Issue 5, May 2014

Pages: 474 - 487

Effect of Massage on Physiological and Behavioral Parameters among Low Birth Weight Babies

Sneha Pitre

Share this article

Research Paper, Medicine Science, India, Volume 6 Issue 8, August 2017

Pages: 510 - 514

A Study on Toxicity and Tolerability of Tenofovir in Tenofovir based First Line Anti Retroviral Therapy in ART Na?ve Patients

Dr MD Mohiuddin Sk, Dr Kapildev Mondal, Dr Subarna Kundu

Share this article
Top