International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 116

Research Paper | Biology | Iraq | Volume 6 Issue 9, September 2017


Estimation of Eugenol Derived Chemical Compound Activity on Intestine Tissue and Some Enzymes of Infected Mice

Noor.A.M. Ajeel, Abdul Latif M. Jawad


Abstract: This research aimed to determine the effect of synthesized chemical derivative of plant extracted and purified eugenol on the intestine of the albino mice infected by Escherichia coli in addition to its effect on liver enzyme ALP and creatinine Phenolic compound eugenol was isolated chemically in laboratory , its purity was confirmed by HPLC technology in percent of 90%- 100%. The purified eugenol was chemically derived producing three new synthesized derivatives derived eugenol compound 1 (D. E. C.1) (methoxy-1- bromo prop-phenol acetate) Experimental animal were used to detect the inhibitory effect of eugenol derivative on pathogenic bacteria E-coli was by injection in vivo. Experiment design included use of 10 mice divided in 5 groups the target organ was (intestine) which was isolated from dissected mice, blood test and biochemical test (Creatinine, Liver enzyme ALP) were performed. Results showed that mice treated twice with D. E. C.1 10% for ALP and creatinine in mice treated twice with D. E. C.1 at 10% was nearly normal value as in the control group. Histological results showed changes in the intestine ranging from hemorrhage, , degeneration and lymphocyte accumulation in infected non- treated mice while the treated mice with D. E. C.1 derivative's showed gradual regeneration after one week.


Keywords: Eugenol, histopathology, biochemical test


Edition: Volume 6 Issue 9, September 2017,


Pages: 120 - 122


How to Cite this Article?

Noor.A.M. Ajeel, Abdul Latif M. Jawad, "Estimation of Eugenol Derived Chemical Compound Activity on Intestine Tissue and Some Enzymes of Infected Mice", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20176405, Volume 6 Issue 9, September 2017, 120 - 122

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'histopathology'

Downloads: 127

Research Paper, Biology, India, Volume 5 Issue 10, October 2016

Pages: 693 - 699

A Study of Histopathogical Examination of Alcohol Induced Hepato-Toxicity in Albino Rats and Protective Effect of Cuminum cyminum

Manash Jyoti Baruah, Prasanta Kr. Baruah, Mridul Kr. Borthakur

Share this Article

Downloads: 130

Research Paper, Biology, India, Volume 5 Issue 10, October 2016

Pages: 804 - 812

Elecrophoretic Pattern and Histopathological Study of Muscle Tissue Tilapia, Oreochromis mossambicus Exposed to Textile Dyes

Vijayalakshmi.M, Sumathy.R, Sharmila.J

Share this Article

Similar Articles with Keyword 'biochemical test'

Downloads: 100

Research Paper, Biology, Iraq, Volume 4 Issue 12, December 2015

Pages: 1938 - 1941

Study of Biochemical Aspects in Women Infected with Trichomonas vaginalis in Babylon Province

Maher Ali ALquraishi, Sura Abdul Khaliq

Share this Article

Downloads: 127

Research Paper, Biology, India, Volume 5 Issue 4, April 2016

Pages: 321 - 324

Characterization of Bacteria Found in Soft-Drink through Biochemical Analysis and 16s rDNA PCR

Ashutosh Kumar Mishra, Pushpasingh, Himani Chugh, Brijesh Lohchania, Monica Srivastava

Share this Article
Top