International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064

Downloads: 116 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Medicine Science | India | Volume 6 Issue 8, August 2017

Spectrum of Precipitating Factors of Hepatic Encephalopathy in Patients with Liver Cirrhosis in Tertiary Care Hospital in North India

Gursewak Singh [3] | Mini Bhatnagar | Amit Saini | Bimal K Agrawal

Abstract: Cirrhosis of liver is a common chronic clinical entity. Hepatic encephalopathy is one of its frequent complication. Often there is an underlying precipitating factor which leads on to encephalopathy. Identifying and managing these factors will improve the quality of life of such patients. Aim- To study patients admitted with hepatic encephalopathy secondary to cirrhosis of liver and to evaluate for the known precipitants. Material and methods- Over a period of one and half year various factors precipitating hepatic encephalopathy in 50 patients with liver cirrhosis were evaluated. Patients were verified for fulfilling inclusion criteria and ruled out for presence of exclusion criteria. Grading of hepatic encephalopathy was done by West Haven Classification and prognostic stratification through Child Pugh score. Results -Gastrointestinal bleed as a precipitant of hepatic encephalopathy was noted among 60 % of patients. Other precipitants include constipation, binge alcohol intake, electrolyte imbalance, infections, overzealous diuretic use, massive paracentesis and use of sedative/psychotropic/hepatotoxic drugs. Most common cause of cirrhosis in this study was alcoholism (66 %).48 % of subjects were grouped in Child Pugh Class C. Conclusion-The result of this study indicates that patients with increased precipitants of hepatic encephalopathy and those who have higher Child Pugh score tend to have worse prognosis. Thus early identification of such precipitating factors and treatment can result in better outcomes. Alcohol emerged as a common cause of cirrhosis of liver and an important precipitating factor for hepatic encephalopathy.

Keywords: hepatic encephalopathy, precipitating factors, liver cirrhosis

Edition: Volume 6 Issue 8, August 2017,

Pages: 1525 - 1528

How to Download this Article?

Type your Email Address Below, Click Anywhere Outside the Box, That will Activate the Download Button

How to Cite this Article?

Gursewak Singh, Mini Bhatnagar, Amit Saini, Bimal K Agrawal, "Spectrum of Precipitating Factors of Hepatic Encephalopathy in Patients with Liver Cirrhosis in Tertiary Care Hospital in North India", International Journal of Science and Research (IJSR), Volume 6 Issue 8, August 2017, pp. 1525-1528,

Similar Articles with Keyword 'hepatic encephalopathy'

Downloads: 87

Case Studies, Medicine Science, India, Volume 8 Issue 11, November 2019

Pages: 1667 - 1668

Kayser Fleischer Ring - An Early Indicator of Wilsons Disease - A Case Study

Mridula V Amarnath [3]

Share this Article

Downloads: 118

Research Paper, Medicine Science, Albania, Volume 4 Issue 11, November 2015

Pages: 1786 - 1789

Different Models of Decompensation in Alcoholic versus Nonalcoholic Cirrhotic Patients

Pranvera Kristani | Floreta Kurti [2] | Sonela Xinxo [2] | Altin Kuqo | Adriana Babameto [3]

Share this Article