Assessment of Toxic Effects of the Endocrine Disruptor Bisphenol-A on Zebra Fish (Danio Rerio) - A Vertebrate System
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Toxicology Science | India | Volume 6 Issue 8, August 2017

Assessment of Toxic Effects of the Endocrine Disruptor Bisphenol-A on Zebra Fish (Danio Rerio) - A Vertebrate System

Mathews P Raj, Jayarama Reddy, Anitha Abraham, Prashanth V

Bisphenol A (BPA) is considered to be one of the important component of plastics, BPA is regarded to be an endocrine disruptor thereby interfering with the production, secretion, transport, action, function and elimination of natural hormones. In the present study the toxic effects of BPA was assessed on mature adult zebra fishes and young fragile embryos. Zebra fishes were grown in reverse osmosis water containing known concentrations of BPA ranging from 0.01Molar (M) to 0.1M. After spawning the young fragile embryos were also subjected to BPA treatment the result of which was mortality of the adult fishes and young embryos. The toxicity of the same was determined in-vivo by measuring the acetyl cholinesterase (AChE) activity in the brain tissue of zebra fish. The results projected a very high AChE activity indicating neuro transmission obstruction and mortality of the zebra fishes.

Keywords: BPA, Acetyl cholinesterase AChE, Zebra fish, plastic toxicology

Edition: Volume 6 Issue 8, August 2017

Pages: 1598 - 1601

Share this Article

How to Cite this Article?

Mathews P Raj, Jayarama Reddy, Anitha Abraham, Prashanth V, "Assessment of Toxic Effects of the Endocrine Disruptor Bisphenol-A on Zebra Fish (Danio Rerio) - A Vertebrate System", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20176129, Volume 6 Issue 8, August 2017, 1598 - 1601

45 PDF Views | 45 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'BPA'

Research Paper, Toxicology Science, India, Volume 6 Issue 8, August 2017

Pages: 1598 - 1601

Assessment of Toxic Effects of the Endocrine Disruptor Bisphenol-A on Zebra Fish (Danio Rerio) - A Vertebrate System

Mathews P Raj, Jayarama Reddy, Anitha Abraham, Prashanth V

Share this Article

Research Paper, Toxicology Science, China, Volume 3 Issue 6, June 2014

Pages: 167 - 172

Correlation between Epididymal Semen Quality Parameters and Malondialdehyde Levels in Adults SD rats Liver after Exposure to Bisphenol A.

Ansoumane Kourouma, Yaima M. Lpez Tamayo, Yang Kedi

Share this Article
Top