Research Paper | Biomedical Sciences | Indonesia | Volume 6 Issue 7, July 2017
High Maternal Serum Interleukin-8 and Endocervical Neutrophil Cell Count as Risk Factors for Preterm Labor
Anak Agung Gede Putra Wiradnyana, Tjokorda Gde Agung Suwardewa, I Ketut Surya Negara
Abstract: Background Preterm labor incidence rates are still high in various countries including Indonesia ranging from 10-20 %. The definite cause of preterm labor remains unknown. IL-8 and neutrophil cell are thought to play important role in the pathogenesis of preterm labor. Objective To determine the role of high maternal serum IL-8 and endocervical neutrophil cell count as risk factors for preterm labor. Study design This is a case control study, involving 46 preterm labor cases and 46 preterm pregnancy controls. Results High level of IL-8 in maternal serum increased the risk of preterm labor by 96 times ( OR =95.56, 95 % CI=22.38-40.87, p = 0.001) compared to low level maternal serum IL8. High number endocervical neutrophil cells increased the risk of preterm labor by 68 times ( OR =68.08, 95 % CI=16.84-275.21, p = 0.001) compared to the low number of neutrophil cells. Maternal serum IL-8 is a more dominant risk factor for preterm labor compared to endocervical neutrophil. Conclusion High level of maternal IL - 8 and endocervical neutrophil cells increase the risk of preterm labor by 96 times and 68 times respectively. Maternal serum IL - 8 is a more dominant risk factor for preterm labor compared to endocervical neutrophil cells.
Keywords: IL - 8, endocervical neutrophil cell, preterm labor
Edition: Volume 6 Issue 7, July 2017,
Pages: 2244 - 2247
How to Cite this Article?
Anak Agung Gede Putra Wiradnyana, Tjokorda Gde Agung Suwardewa, I Ketut Surya Negara, "High Maternal Serum Interleukin-8 and Endocervical Neutrophil Cell Count as Risk Factors for Preterm Labor", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20175894, Volume 6 Issue 7, July 2017, 2244 - 2247
How to Share this Article?
Similar Articles with Keyword 'IL'
To Identify and Examine the Different Causes of Liver Disease in Sri Lanka
Fahim Aslam, Hashan Kulasena
Evolutionary Profile of Drepanocytic Patients Followed at the National Drepanocytosis Reference Centre (CNRDr) Congo Brazzaville
Edwige Paola Chancelle LOUANGA NANITELAMIO, Serge Oscar MOKONO, Chaldam Jesp?re MBANI, Olivia Galiba Atipo - Tsiba, Fabien Roch NIAMA, Etienne MOKONDJIMOBE, Donatien MOUKASSA, Ange Antoine ABENA, Alexis ELIRA DOKEKIAS