RP-HPLC Method Development and Validation for the Analyisis of Pharmaceutical Drug ? ACECLOFENAC
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
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Research Paper | Chemistry | India | Volume 6 Issue 7, July 2017

RP-HPLC Method Development and Validation for the Analyisis of Pharmaceutical Drug ? ACECLOFENAC

Ami R Patel, Dr. V G Patel

A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of ACECLOFENAC. Isocratic elution at a flow rate of 1.2 ml /min was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile 0.1M Acetic Acid 6040 (v/v). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 0.01-0.05 gm/ml. The retention time for ACECLOFENAC was 3.0 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of ACECLOENAC.

Keywords: Aceclofenac, Method Development, Validation, 210nm, 30min

Edition: Volume 6 Issue 7, July 2017

Pages: 1318 - 1320

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Ami R Patel, Dr. V G Patel, "RP-HPLC Method Development and Validation for the Analyisis of Pharmaceutical Drug ? ACECLOFENAC", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20175544, Volume 6 Issue 7, July 2017, 1318 - 1320

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