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Research Paper | Biological Sciences | India | Volume 6 Issue 7, July 2017

Evaluation of Clinical Outcome and Estimation of Effect of Serum Creatinine Levels in Parkinson's Patients with the Administration of Ropinirole

Mathew George ^[4] | Lincy Joseph ^[2] | Ashna Sali

Abstract: Parkinsons disease is a long term degenerative disorder of the central nervous system that mainly affects the motor system. Dopamine agonists are used in the treatment of parkinsons disease. Ropinirole is a dopamine agonist used in the treatment of parkinsons disease. The present review is aimed on the evaluation of clinical outcome and estimation of serum creatinine levels in parkinsons patients with the sdministration of ropinirole. The clinical monitoring of serum creatinine levels is done to estimate the safety and efficacy of ropinirole in the treatment of Parkinsons disorder. After the study it was found that the serum creatinine levels were significantly increased in patients administered with ropinirole and the levels remained normal in patients administered with ropinirole. The review provides information regarding the side effects, drug interaction of ropinirole and also the comorbidities of the disease. The review states the use of other anti parkinsons drugs instead of ropinirole i. e. levodopa or the dose may be reduced.

Keywords: Parkinsons disease, Creatinine, Ropinirole, Dopamine agonists, Levodpoa

Edition: Volume 6 Issue 7, July 2017,

Pages: 1105 - 1111

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