International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 96

Review Papers | Clinical Chemistry | Bulgaria | Volume 6 Issue 6, June 2017


Serum Proteins Electrophoresis by Agarose Gel ? M-Spike Screening and Beyond - Review

Julieta Hristova, Mariana Genova


Abstract: Serum protein electrophoresis (SPE) is a laboratory technique used as a screening test for dysproteinemia. One of the most commonly used media is agarose presenting excellent visualization and densitometric quantification. Clinical presentation of diseases related to monoclonal protein is often obscure at the onset and the complications are the first to come forward in an advanced disease. SPE is also included in different diagnostic panels as a helpful diagnostic tool in the context of liver diseases, nephrotic syndrome, acute and chronic inflammation, hemolytic anemia, iron-deficiency anemia, hyperlipidemia, and polyclonal gammopathies.


Keywords: serum protein electrophoresis, agarose gel, dysproteinemia, monoclonal gammopathy


Edition: Volume 6 Issue 6, June 2017,


Pages: 1463 - 1466


How to Cite this Article?

Julieta Hristova, Mariana Genova, "Serum Proteins Electrophoresis by Agarose Gel ? M-Spike Screening and Beyond - Review", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20174579, Volume 6 Issue 6, June 2017, 1463 - 1466

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