Effect of Mancozeb on the Specific activities of Testicular Steroidogenic Enzymes (3?-HSD, 17?-HSD) and Protective role of Vitamin C in Albino Rats
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Research Paper | Zoology | India | Volume 6 Issue 5, May 2017

Effect of Mancozeb on the Specific activities of Testicular Steroidogenic Enzymes (3?-HSD, 17?-HSD) and Protective role of Vitamin C in Albino Rats

Dr. Ananthan, Dr. G. Ananthan

Mancozeb, an Inorganic-zinc dithiocarbamate is a typical fungicide with carbamate structure. It is chemically identified as ethylenebisdithiocarbamate (EBDC). It is commonly used for foliar application and seed treatment in agriculture. The present work was conducted to assess the protective effect of vitamin C against Mancozeb induced toxicity in the Testicular activity of adult albino rats. 90 days old adult Male wister albino rats (Rattus norvegicus) were exposed to Mancozeb at the dose of 300mg/kg body weight, orally for 60 days. The control group received olive oil. Administration of Mancozeb significantly decreased (p<0.05) the activities of 3-hydroxysteroid dehydrogenase (3-HSD) and 17- hydroxysteroid dehydrogenase (17-HSD), compared to control. Co-administration of vitamin-C with Mancozeb restored the activities of the enzymes to normalcy. The withdrawal group of Mancozeb toxic effect was reversible. The present study reveals that the protective effect of vitamin C on the Mancozeb induced testicular toxicity in adult rats.

Keywords: Mancozeb, Vitamin C, 3- and 17 - Hydroxysteroid dehydrogen ase 3-HSD, 17-HSD, Testes

Edition: Volume 6 Issue 5, May 2017

Pages: 2170 - 2173

Share this Article

How to Cite this Article?

Dr. Ananthan, Dr. G. Ananthan, "Effect of Mancozeb on the Specific activities of Testicular Steroidogenic Enzymes (3?-HSD, 17?-HSD) and Protective role of Vitamin C in Albino Rats", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20173597, Volume 6 Issue 5, May 2017, 2170 - 2173

80 PDF Views | 78 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Vitamin C'

Research Paper, Zoology, India, Volume 6 Issue 5, May 2017

Pages: 1988 - 1992

Role of Vitamin C in Attenuation of Carbon Tetrachloride Induced Toxicity in Heart of Mice

Sushma Sharma, Babita Kumari

Share this Article

Research Paper, Zoology, India, Volume 9 Issue 4, April 2020

Pages: 1416 - 1420

Phytochemical Analysis, Antioxidant and Antihemolytic Activity of Hibiscus and Amla

Deepak T, Shashank A S, K Yeshwanth Kumar, Vinanthi Rajalakshmi K S

Share this Article

Research Paper, Zoology, India, Volume 6 Issue 5, May 2017

Pages: 1050 - 1056

Protective Effect of Vitamin C on Carbon Tetrachloride Administered Toxicity in Lungs of Mice

Sushma Sharma, Sonika Chauhan

Share this Article

Research Paper, Zoology, India, Volume 6 Issue 5, May 2017

Pages: 2170 - 2173

Effect of Mancozeb on the Specific activities of Testicular Steroidogenic Enzymes (3?-HSD, 17?-HSD) and Protective role of Vitamin C in Albino Rats

Dr. Ananthan, Dr. G. Ananthan

Share this Article

Research Paper, Zoology, India, Volume 7 Issue 10, October 2018

Pages: 115 - 117

Effects of Vitamin C on Protein Profiles of Silk Worm, Bombyx mori LXCSR2 and Pure Mysore

Sundara Raj J, W. Kerenhap Evangelin, S Akhil Kumar

Share this Article

Similar Articles with Keyword 'Testes'

Research Paper, Zoology, Pakistan, Volume 3 Issue 9, September 2014

Pages: 2064 - 2066

Bicotylophora blochii n. sp (Monogenea: Discocotylidae) from the Gills of Trachinotus blochii of Karachi Coast, Pakistan

Rana Hadi, Fatima Mujib Bilqees

Share this Article

Research Paper, Zoology, India, Volume 4 Issue 5, May 2015

Pages: 788 - 790

Lipid alteration in Testes and Male Accessory Glands of Leucopholis lepidophora

Suvarna B. More

Share this Article

Research Paper, Zoology, India, Volume 9 Issue 4, April 2020

Pages: 1477 - 1479

New Species Stilesia Ganeshraroji n.sp. (Eucestoda: Thysanomidae) Fuhrmann, 1907 from Capra hircus L. Parbhani (M.S.) India

B. G. Thakare

Share this Article

Research Paper, Zoology, India, Volume 6 Issue 5, May 2017

Pages: 2170 - 2173

Effect of Mancozeb on the Specific activities of Testicular Steroidogenic Enzymes (3?-HSD, 17?-HSD) and Protective role of Vitamin C in Albino Rats

Dr. Ananthan, Dr. G. Ananthan

Share this Article
Top