International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 120 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Mathematics | Morocco | Volume 6 Issue 4, April 2017


The Optimal Impulsive Drug Schedule for Cancer Immunotherapy

Samira Zouhri, Smahane Saadi, Amine Hamdache


Abstract: The aim of this work is to resolve the problem of finding the optimal therapeutic protocols in cancer immunotherapy including the best dosage and timing of immunotherapy drug. We formulate this problem as an optimization problem by applying the theory of optimal impulsive control using a mathematical model of five ordinary differential equations that describe the kinetics of several populations (tumor cells and three types of immune cells) as well as the intervention of immunotherapy with interleukin2.


Keywords: immunotherapy Interleukin-2 impulsive optimal control drug schedule


Edition: Volume 6 Issue 4, April 2017,


Pages: 1643 - 1652


How to Cite this Article?

Samira Zouhri, Smahane Saadi, Amine Hamdache, "The Optimal Impulsive Drug Schedule for Cancer Immunotherapy", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20172431, Volume 6 Issue 4, April 2017, 1643 - 1652

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'impulsive'

Downloads: 102

Research Paper, Mathematics, Iraq, Volume 6 Issue 6, June 2017

Pages: 801 - 805

Precise Solutions of a Viscoelastic Fluid Flow in an Annular Pipe under an Impulsive Pressure with the Fractional Generalized Burgers Model

Hanan F. Qasim, Ghada H. Ibraheem

Share this Article

Downloads: 137

Research Paper, Mathematics, India, Volume 4 Issue 7, July 2015

Pages: 150 - 159

Existence Results for Partial Integro-Differential Equations in Banach Spaces

G. Selvam, K. Mathevan Pillai

Share this Article

Similar Articles with Keyword 'optimal'

Downloads: 146

Research Paper, Mathematics, India, Volume 6 Issue 11, November 2017

Pages: 1792 - 1796

A Study on Graph with Desmos through ICT in Diploma in Elementary Education of Tamil Nadu State Board

P. Charles Paul, G. Thulasi

Share this Article

Downloads: 161 | Monthly Hits: ⮙1

Research Paper, Mathematics, Nigeria, Volume 6 Issue 8, August 2017

Pages: 1893 - 1895

Integer Linear Programming Applied to Nurses Rostering Problem

A. A. Maidamisa, H. A. Odiniya

Share this Article

Similar Articles with Keyword 'control'

Downloads: 1

Research Paper, Mathematics, Congo (DRC), Volume 10 Issue 5, May 2021

Pages: 571 - 577

Solvency and Reinsurance Treaty of an Automobile Portfolio: Case of Sub-Saharian Countries

Bukanga Maheshe Crispin, Mabela Makengo Matendo Rostin

Share this Article

Downloads: 5

Research Paper, Mathematics, Kenya, Volume 10 Issue 6, June 2021

Pages: 126 - 131

Modified Navier-Stokes Equation for Incompressible Fluid Impacts

Hagai Amakobe James

Share this Article

Similar Articles with Keyword 'drug'

Downloads: 64

Research Paper, Mathematics, Botswana, Volume 10 Issue 1, January 2021

Pages: 919 - 936

Mathematical Analysis of a Model with HIV-1 Mutation in the Midst of a Cellular Immune Response

Obias Chimbola Mulenga

Share this Article

Downloads: 116

Research Paper, Mathematics, Nigeria, Volume 7 Issue 7, July 2018

Pages: 1067 - 1069

Modeling the Effect of Coincident Drug-Release Rate and Absorption in Intestinal Lumen

Enobong E. Joshua, Ubon A. Abasiekwere

Share this Article

Similar Articles with Keyword 'schedule'

Downloads: 161 | Monthly Hits: ⮙1

Research Paper, Mathematics, Nigeria, Volume 6 Issue 8, August 2017

Pages: 1893 - 1895

Integer Linear Programming Applied to Nurses Rostering Problem

A. A. Maidamisa, H. A. Odiniya

Share this Article

Downloads: 2

Research Paper, Mathematics, India, Volume 10 Issue 9, September 2021

Pages: 1107 - 1111

Mathematical Model on Reliability with Three Units

Dr. Shruti Rani

Share this Article
Top