International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 103

Research Paper | Cardiology Science | Egypt | Volume 6 Issue 2, February 2017


The Value of Serum Apelin Measurement in Acute Coronary Syndrome Patients

Ahmed Hamouda Arnaout, Iman Esmat Ibrahim, Lamya Mahmoud Ibrahim


Abstract: Introduction Acute coronary syndrome refers to any group of clinical symptoms compatible with acute myocardial ischemia including unstable angina (UA), NonST segment elevation myocardial infarction (NSTEMI), and ST segment elevation myocardial infarction (STEMI). Apelin is an endogenous peptide with inotropic and vasodilatory properties, it was recently reported that serum measurements of apelin were similar to its immunohistochemical data in vessels and heart tissues. Aim of the study To detect the value of the serum levels of apelin in patients with Acute Coronary Syndrome related to severity of presentation. Patients and methods 59 patients with Acute Coronary Syndrome (ACS) were included in the study during the period from January until July 2016, as 30 patients with UA, 15 with NSTEMI, and 14 with STEMI. Also the study included 28 apparently healthy persons as control. Blood samples were obtained for measurements of Apelin by ELISA method. Results Serum apelin levels were significantly decreased in whole group of patients with ACS (1846.1320.9) ng/ml compared to control (2719.4272.5) ng/ml (p < 0.05). Regarding patients subgroups, serum apelin was lowest in STEMI (1729.0480.0) ng/ml, NSTEMI (1816.0289.0) ng/ml, and UA (1916.0224.4) ng/ml when compared with control, respectively. Conclusions The value of serum apelin levels significantly reduced in all patients groups especially STEMI, so it could be considered as a biochemical marker for evaluation of ACS. Acute Coronary Syndrome, Unstable angina, ST segment elevation MI, Non ST segment elevation MI, Apelin.


Keywords: Acute Coronary Syndrome, Unstable angina, ST segment elevation MI, Non ST segment elevation MI, Apelin


Edition: Volume 6 Issue 2, February 2017,


Pages: 1292 - 1294


How to Cite this Article?

Ahmed Hamouda Arnaout, Iman Esmat Ibrahim, Lamya Mahmoud Ibrahim, "The Value of Serum Apelin Measurement in Acute Coronary Syndrome Patients", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20171020, Volume 6 Issue 2, February 2017, 1292 - 1294

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Acute Coronary Syndrome'

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article

Downloads: 14

Comparative Studies, Cardiology Science, India, Volume 10 Issue 4, April 2021

Pages: 622 - 625

Elevated hs TROPONIN -I in RT-PCR Positive COVID-19 Patients without Cardiac Symptoms

M. Anuradha, Biju Govind, John R Satish

Share this Article

Similar Articles with Keyword 'Unstable angina'

Downloads: 103

Research Paper, Cardiology Science, India, Volume 4 Issue 11, November 2015

Pages: 2235 - 2239

Association between Accessory Nipple and Coronary Artery Disease

Dr Prabhu C Halkati, Dr Suresh V Patted, Dr Vishwanath Hesarur, Dr Sanjay C Porwal, Dr Sameer Ambar, Dr Ameet Sattur

Share this Article

Downloads: 109

Research Paper, Cardiology Science, India, Volume 3 Issue 8, August 2014

Pages: 551 - 553

Role of CK-MB and Troponin-I in Diagnosing Non-ST-Elevation Myocardial Infarction

Kiran R Bagale, Avinash S. Ingle

Share this Article

Similar Articles with Keyword 'Acute'

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article

Downloads: 1

Case Studies, Cardiology Science, Indonesia, Volume 10 Issue 5, May 2021

Pages: 1049 - 1051

Women with Persistent Left Ventricular Systolic Dysfunctionin Peripartum Cardiomyopathy - A Case Report

I Putu Adi Palguna, I Gusti Ayu Suryawati

Share this Article

Similar Articles with Keyword 'Coronary'

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Cardiology Science, Romania, Volume 10 Issue 11, November 2021

Pages: 450 - 454

Coronary Angiography by CT Accuracy for the Chronic Coronary Disease Diagnosis

Livia Trasca, Catalina Paraschiv, Liviu Ghilencea, Camelia Georgescu, Olguta Ileana Rizea, Amal Alam, Andreea Catarina Popescu

Share this Article

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article

Similar Articles with Keyword 'Syndrome'

Downloads: 0

Case Studies, Cardiology Science, Morocco, Volume 10 Issue 5, May 2021

Pages: 513 - 516

Unwelcomed Guest to the Heart: Secondary Cardiac Localization of Non-Hodgkin's Lymphoma: About a Case and Review of Literature

Soumia Faid, Amina Samih, Nadif Meryem, Nadia Loudiyi, Zaimi Achraf, Najat Mouine, Ilyass Asfalou, Aatif Benyass

Share this Article

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article

Similar Articles with Keyword 'Unstable'

Downloads: 2 | Monthly Hits: ⮙2

Case Studies, Cardiology Science, Morocco, Volume 10 Issue 10, October 2021

Pages: 1049 - 1051

Cholesterol Crystal Embolisms Complicating Coronary Artery Bypass Surgery: One Case Report

A. Seghrouchni, N. Atmani, Y. Moutakiallah

Share this Article

Downloads: 103

Research Paper, Cardiology Science, India, Volume 4 Issue 11, November 2015

Pages: 2235 - 2239

Association between Accessory Nipple and Coronary Artery Disease

Dr Prabhu C Halkati, Dr Suresh V Patted, Dr Vishwanath Hesarur, Dr Sanjay C Porwal, Dr Sameer Ambar, Dr Ameet Sattur

Share this Article

Similar Articles with Keyword 'angina'

Downloads: 102

Research Paper, Cardiology Science, Bangladesh, Volume 4 Issue 4, April 2015

Pages: 2081 - 2085

AHC/ACC Stenosis Morphology Classification Based Comparison of Coronary Angiographic Lesions in Patients with Acute Coronary Syndrome (ACS) and Chronic Stable Angina (CSA) in a Tertiary Care Centre

Tanjima Parvin, Nafiza Ahmed, Ifat Ara Begum, KMHS Sirajul Haque

Share this Article

Downloads: 103

Research Paper, Cardiology Science, India, Volume 4 Issue 11, November 2015

Pages: 2235 - 2239

Association between Accessory Nipple and Coronary Artery Disease

Dr Prabhu C Halkati, Dr Suresh V Patted, Dr Vishwanath Hesarur, Dr Sanjay C Porwal, Dr Sameer Ambar, Dr Ameet Sattur

Share this Article

Similar Articles with Keyword 'ST'

Downloads: 0

Case Studies, Cardiology Science, Morocco, Volume 10 Issue 5, May 2021

Pages: 513 - 516

Unwelcomed Guest to the Heart: Secondary Cardiac Localization of Non-Hodgkin's Lymphoma: About a Case and Review of Literature

Soumia Faid, Amina Samih, Nadif Meryem, Nadia Loudiyi, Zaimi Achraf, Najat Mouine, Ilyass Asfalou, Aatif Benyass

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Cardiology Science, Romania, Volume 10 Issue 11, November 2021

Pages: 450 - 454

Coronary Angiography by CT Accuracy for the Chronic Coronary Disease Diagnosis

Livia Trasca, Catalina Paraschiv, Liviu Ghilencea, Camelia Georgescu, Olguta Ileana Rizea, Amal Alam, Andreea Catarina Popescu

Share this Article

Similar Articles with Keyword 'segment'

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 7, July 2021

Pages: 1424 - 1427

Arterial Injuries in Children with Supracondylar Fracture of the Humerus - Our Institutional Experience

Dr. K Sudhakar Rao, Dr. Harivadan Lukka, Dr. Manitha Kondru, Dr. K Sivananda

Share this Article

Downloads: 1

Informative Article, Cardiology Science, India, Volume 10 Issue 9, September 2021

Pages: 1415 - 1417

A Descriptive Study: - 2D - Echocardiography and Coronary Angiography Changes of RBBB in Acute Myocardial Infarction

Nishel Yogesh Kothari, Rajiv Girdhar, Ram Anil Raj

Share this Article

Similar Articles with Keyword 'elevation'

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article

Downloads: 1

Informative Article, Cardiology Science, India, Volume 10 Issue 9, September 2021

Pages: 1415 - 1417

A Descriptive Study: - 2D - Echocardiography and Coronary Angiography Changes of RBBB in Acute Myocardial Infarction

Nishel Yogesh Kothari, Rajiv Girdhar, Ram Anil Raj

Share this Article

Similar Articles with Keyword 'MI'

Downloads: 0

Case Studies, Cardiology Science, Morocco, Volume 10 Issue 5, May 2021

Pages: 513 - 516

Unwelcomed Guest to the Heart: Secondary Cardiac Localization of Non-Hodgkin's Lymphoma: About a Case and Review of Literature

Soumia Faid, Amina Samih, Nadif Meryem, Nadia Loudiyi, Zaimi Achraf, Najat Mouine, Ilyass Asfalou, Aatif Benyass

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Cardiology Science, Romania, Volume 10 Issue 11, November 2021

Pages: 450 - 454

Coronary Angiography by CT Accuracy for the Chronic Coronary Disease Diagnosis

Livia Trasca, Catalina Paraschiv, Liviu Ghilencea, Camelia Georgescu, Olguta Ileana Rizea, Amal Alam, Andreea Catarina Popescu

Share this Article

Similar Articles with Keyword 'Non'

Downloads: 0

Case Studies, Cardiology Science, Morocco, Volume 10 Issue 5, May 2021

Pages: 513 - 516

Unwelcomed Guest to the Heart: Secondary Cardiac Localization of Non-Hodgkin's Lymphoma: About a Case and Review of Literature

Soumia Faid, Amina Samih, Nadif Meryem, Nadia Loudiyi, Zaimi Achraf, Najat Mouine, Ilyass Asfalou, Aatif Benyass

Share this Article

Downloads: 1

Research Paper, Cardiology Science, India, Volume 10 Issue 5, May 2021

Pages: 1004 - 1009

Clinical Outcomes of Chronic Kidney Disease Patients with STEMI Treated with Percutaneous Coronary Intervention: A Single Centre Study

Krishnakumar Prabhakaran, Mathew Iype, Prabha Nini Gupta, Sunitha Viswanathan

Share this Article
Top