International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 108

Case Studies | Medicine Science | India | Volume 6 Issue 1, January 2017


A Case of Myasthenia Gravis Presenting Solely with Bulbar Palsy not associated with Easy Fatigability

Dr. Patel J. J. | Dr. Singh V. P. | Dr. Chauhan P.


Abstract: Myesthenia Gravis (MG) is a neuromuscular disorder characterized by weakness and fatigability of skeletal muscles as a result of decrease in numbers of available acetylcholine receptors (AChRs) at neuromuscular junction due to an antibody-mediated autoimmune attack. We present here male case of Myesthenia Gravis who presented with complaints of unable to drink water and coming out from nose while swallowing. Gradually he developed inability to eat.2 months later patient developed slurring of speech followed by total inability to speak. Also developed diplopia on binocular vision. On cranial nerve examination 3, 7, 9, 10th nerve palsies seen in the form of absence of medial & upward movement of left eye (3rd C. N. ), inability to close eyes completely (3rd C. N. ), reduced power and tone of buccinators muscle (7th C. N. ), gag reflex absent (9th C. N. ), presence of dysphagia (10th C. N. ). Rest of the CNS findings were normal. ANA was (+) with nuclear speckled pattern. VEP study was normal. EMG NCV showed reduced amplitude of bilateral facial nerve, involvement of right oculomotor nerve suggesting bulbar myasthenia >generalized myasthenia. Then we did AChR antibody test which came highly positive. He was started T. Pyridostigmine 60mg TDS and T. Prednisolone 5mg/kg and discharged. On follow up we found marked improvement of symptoms.


Keywords: Myesthenia Gravis, Acetylcholine Receptors AChRs, Cranial Nerve CN, Muscle-specific tyrosine kinase MuSK, Dysphagia, Gag Reflex


Edition: Volume 6 Issue 1, January 2017,


Pages: 2265 - 2266

A Case of Myasthenia Gravis Presenting Solely with Bulbar Palsy not associated with Easy Fatigability


How to Cite this Article?

Dr. Patel J. J., Dr. Singh V. P., Dr. Chauhan P., "A Case of Myasthenia Gravis Presenting Solely with Bulbar Palsy not associated with Easy Fatigability", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART201646881, Volume 6 Issue 1, January 2017, 2265 - 2266, #ijsrnet

How to Share this Article?

Enter Your Email Address




Similar Articles with Keyword 'Dysphagia'

Downloads: 118

Research Paper, Medicine Science, Mexico, Volume 6 Issue 10, October 2017

Pages: 1141 - 1147

Prevalence of Swallowing Disorders and Its Association with Geriatric Syndromes in Elderly Patients Attending to a First Level Care Center

Diaz-Ramos Julio Alberto | Mondragon-Cervantes Martha Ivon | Jimenez-Acosta Yenesis del Carmen | Fraga-Avila Claudia | Diaz-Garcia Irma Fabiola | Coss-Adame Enrique | Leal-Mora David

Share this Article

Downloads: 133

Research Paper, Medicine Science, India, Volume 2 Issue 12, December 2013

Pages: 90 - 91

Anaesthetic Management of a Large Atypical Antrochoanal Polyp for FESS

Ravi Prakash [6] | V. K. Bhatia

Share this Article


Top