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Research Paper | Applied Chemistry | Morocco | Volume 6 Issue 8, August 2017
Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides
Z. Tribak  | M.K. Skalli | O. Senhaji  | Y. Kandri Rodi 
Abstract: A new series of dioxazoline of 5-Chloroisatin derivatives has been designed and synthesized involving 1, 3-dipolar cycloaddition reaction, preceded by a simple N-alkylation reaction in phase-transfer catalytic conditions The regioselectivity of the reactions was ascertained by 1H, 13C NMR spectroscopy of the synthesized compounds.
Keywords: 5-Chloroisatin, Dioxazoline, N-alkylation, 1, 3-Dipolar cycloaddition, 1H, 13C NMR spectroscopy
Edition: Volume 6 Issue 8, August 2017,
Pages: 1145 - 1149
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