International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 129

Research Paper | Marine Environment | Morocco | Volume 6 Issue 2, February 2017


Lipophilic Toxin Profile in Mytilus galloprovincialis from the North Atlantic Coast of Morocco: LC-MS/MS and Mouse Bioassay Analyses

Asia Ben Haddouch, Rachid Amanhi, Zouher Amzil, Hamid Taleb, Georges Rovillon, Farida Adly, Mohammed Loutfi


Abstract: For the Moroccan Phycotoxins Monitoring that is part of the Safety of the Coastal Monitoring Network (RSSL), shellfish samples were harvested from different locations at North Atlantic of Morocco where harmful algae blooms were known to have occurred. For all shellfish samples found positive by the mouse bioassay for diarrheic shellfish poisoning (DSP) toxins, liquid chromatography coupled to tandem mass spectrometry (LC-MS-MS) in order to search the following lipophilic toxins okadaic acid (OA), dinophysistoxins (DTXs), pectenotoxins (PTXs), azaspiracids (AZAs), yessotoxins (YTXs), spirolides (SPXs) and gymnodimines (GYMs). The results revealed different lipophilic toxin profiles as a function of the shellfish sampling location. It has been noticed that all the samples contained OA and its derivatives named dinophysistoxins (DTXs). In addition, other lipophilic toxins were found in shellfish samples (YTXs), and pectenotoxins (PTX-2, PTX-2-seco-acid and 7- epi-PTX-2-seco-acid) on the North Atlantic coast. This paper reports on the first detection of YTXs, PTXs GYMs and their derivatives in Moroccan shellfish.


Keywords: diarrheic toxins, lipophilic toxins, LC-MS/MS, mouse test, shellfish


Edition: Volume 6 Issue 2, February 2017,


Pages: 186 - 195


How to Cite this Article?

Asia Ben Haddouch, Rachid Amanhi, Zouher Amzil, Hamid Taleb, Georges Rovillon, Farida Adly, Mohammed Loutfi, "Lipophilic Toxin Profile in Mytilus galloprovincialis from the North Atlantic Coast of Morocco: LC-MS/MS and Mouse Bioassay Analyses", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=24121602, Volume 6 Issue 2, February 2017, 186 - 195

How to Share this Article?

Enter Your Email Address


Top