Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Downloads: 98

Research Paper | Biology | Algeria | Volume 3 Issue 8, August 2014

Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring

Meriem Haloui, Abdelkrim Tahraoui

The present study aims to put some tracks values especially with regard to the likely transmission over generations of cognitive and behavioural damages. This by investigating the effects of chronic restraint stress (1hour /day, 4 days / week for 5 weeks) applied before gestation in mothers on the generation of anxiety and depression-like behaviours and their effects on the hypothalomo-pitutary-gonadotroph HPG axis by measuring the concentration of progesterone in rats after stress. After birth, the development of the offspring was studied. Our results show that chronic restraint stress involved a development of anxiety in the Elevated Plus maze test (EPM) (anxiety like behaviour), increased immobility during Forced swimming test (FST) (depression like behaviour). Disturbances of the HPG axis were revealed by the highly significant elevation of plasma progesterone concentration. The offspring male and female chowed hyperactivity disorder in the Open Field test (OF) at the age of adolescence.

Keywords: Chronic Restraint Stress, Anxiety, Depression, HPG axis, Offspring, Neurobehavioural Disorders

Edition: Volume 3 Issue 8, August 2014

Pages: 1963 - 1968

Share this Article

How to Cite this Article?

Meriem Haloui, Abdelkrim Tahraoui, "Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=2015734, Volume 3 Issue 8, August 2014, 1963 - 1968

Enter Your Email Address




Similar Articles with Keyword 'Anxiety'

Downloads: 98

Research Paper, Biology, Algeria, Volume 3 Issue 8, August 2014

Pages: 1963 - 1968

Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring

Meriem Haloui, Abdelkrim Tahraoui

Share this Article

Downloads: 114

Research Paper, Biology, India, Volume 4 Issue 9, September 2015

Pages: 867 - 868

Effectiveness of Relaxation Technique to Reduce Stress among Drivers

R. Priyanka, S. Tamilselvi

Share this Article

Similar Articles with Keyword 'Depression'

Downloads: 98

Research Paper, Biology, Algeria, Volume 3 Issue 8, August 2014

Pages: 1963 - 1968

Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring

Meriem Haloui, Abdelkrim Tahraoui

Share this Article

Downloads: 159

Case Studies, Biology, India, Volume 6 Issue 8, August 2017

Pages: 30 - 33

Surrogacy and Health Issues

Dr. Jyotsna Jain

Share this Article

Similar Articles with Keyword 'Offspring'

Downloads: 98

Research Paper, Biology, Algeria, Volume 3 Issue 8, August 2014

Pages: 1963 - 1968

Effects of Pregestational Chronic Restraint Stress on the Generation of Psychological and Neurobehavioural Disorders in Female Wistar Rats and their Offspring

Meriem Haloui, Abdelkrim Tahraoui

Share this Article

Downloads: 109

Review Papers, Biology, India, Volume 4 Issue 5, May 2015

Pages: 2203 - 2207

Prevalence of Consanguinity in Muslim Community-A Review

Shamshad. S

Share this Article

Downloads: 112 | Monthly Hits: ⮙7

Research Paper, Biology, Iraq, Volume 4 Issue 5, May 2015

Pages: 2248 - 2250

Blood Parameters that Affect Awasi Sheep Production

S. H. Alsamarrae

Share this Article

Downloads: 126

Research Paper, Biology, India, Volume 6 Issue 1, January 2017

Pages: 1591 - 1593

Fig Tree with Unrelated Fig Wasps

Aravind Krishnan K., Gayathri G. S., Sreedevi Amma

Share this Article



Top