Comparative Evaluation of Efficacy of Transdermal Diclofenac Patch, Eutectic Mixture of Local Anaesthetic Cream and Placebo for Venous Cannulation Pain and Attenuation of Hemodynamic Response
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Views: 160 , Downloads: 127 | CTR: 79 % | Weekly Popularity: ⮙4

Research Paper | Medicine Science | India | Volume 3 Issue 2, February 2014

Comparative Evaluation of Efficacy of Transdermal Diclofenac Patch, Eutectic Mixture of Local Anaesthetic Cream and Placebo for Venous Cannulation Pain and Attenuation of Hemodynamic Response

Shobha D, Parashuram Jajee

Purpose: Venous cannulation is painful and associated with a high incidence of vasovagal and pressor responses. The aim of this study is to evaluate the efficacy of transdermal diclofenac patch (TDP) and eutectic mixture of local anaesthetics (EMLA) cream for intravenous cannulation pain and to attenuate the haemodynamic response to it. Methods: This was a prospective, randomized, double blind, placebo controlled study in which 102 adult ASA I and II patients undergoing elective surgery of both sexes were divided into three groups. Group P received placebo cream, Group E received EMLA cream 2gm/10cm2 and Group D received TDP 100mg/50cm2, at the proposed site, 60min prior to the insertion of a 18G IV cannula. The resulting pain was assessed by VAS. The heart rate and blood pressure was recorded before and at 1min of Intravenous cannulation to assess the stress response. Results: TDP and EMLA cream were effective in reducing both the incidence and severity of pain in comparison to the placebo group and also attenuated the stress response to it. Conclusion: TDP can be used as an alternative to EMLA cream for reducing the incidence and severity of venous cannulation pain and for attenuating the haemodynamic response, in patients who are sensitive to EMLA cream.

Keywords: Transdermal Diclofenac Patch, Eutectic mixture of local anaesthetics cream, Intravenous cannulation, Haemodynamic stress response

Edition: Volume 3 Issue 2, February 2014

Pages: 17 - 20

Share this Article

How to Cite this Article?

Shobha D, Parashuram Jajee, "Comparative Evaluation of Efficacy of Transdermal Diclofenac Patch, Eutectic Mixture of Local Anaesthetic Cream and Placebo for Venous Cannulation Pain and Attenuation of Hemodynamic Response ", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=2013802, Volume 3 Issue 2, February 2014, 17 - 20

160 PDF Views | 127 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Intravenous cannulation'

Views: 146 , Downloads: 124 | CTR: 85 % | Weekly Popularity: ⮙1

Research Paper, Medicine Science, Saudi Arabia, Volume 5 Issue 12, December 2016

Pages: 1815 - 1817

Efficacy of Topical Anesthesia Cream in Reducing the Pain Associated with Intravenous Cannulation

Pushpamala Ramaiah, Dr. Lamiaa Ahmed Elsayed, Dr. Hamdia Mohammed Abdelaziz Khamis

Share this Article

Views: 160 , Downloads: 127 | CTR: 79 % | Weekly Popularity: ⮙4

Research Paper, Medicine Science, India, Volume 3 Issue 2, February 2014

Pages: 17 - 20

Comparative Evaluation of Efficacy of Transdermal Diclofenac Patch, Eutectic Mixture of Local Anaesthetic Cream and Placebo for Venous Cannulation Pain and Attenuation of Hemodynamic Response

Shobha D, Parashuram Jajee

Share this Article
Top