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Research Paper | Biology | India | Volume 4 Issue 12, December 2015 | Rating: 6.2 / 10
Cytotoxicity Analysis of Crude Leaf Extracts from Tecoma castanifolia (D. Don) Melch on Brine Shrimp and MCF-7 Cell Line
R. Vidhya, Dr. Albin T. Fleming
Abstract: To assess the possibility of cytotoxic potential of T. castanifolia leaf extract. Since this family of plants have effective cytotoxic potential against cancer, analysis of this particular species was carried out. The acetone, ethylacetate and ethanol extracts were subjected to brine shrimp lethality assay and cytotoxicity analysis against MCF-7 cell line. MTT assay of these three extracts showed the ethyl acetate extract to be most effectively cytotoxic. Further studies can be carried out in this aspect to bring out the complete effectiveness of the extract and compounds therein.
Keywords: Plant extract, cytotoxicity, Brine shrimp, MCF-7, MTT assay
Edition: Volume 4 Issue 12, December 2015,
Pages: 1405 - 1408