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Syntheses, Characterization and Antimicrobial Activity of Triphenyl Antimony (V) Derivatives of Heterocyclic Dithiocarbamate

Deepak Kumar Sharma, Jyoti Sharma, Ramavatar Sharma

Abstract: The reactions of Ph3SbBr2 with the sodium salt of heterocyclic dithiocarbamates in 1:1 and 1:2 stoichiometries yield the derivatives and , respectively [Where X = >CH2 (Pipdtc) (1,6), >CHCH3 (4-MePipdtc) (2,7), >O (Morphdtc) (3,8), >N-CH3 (N-mePzdtc) (4,9) and >NH (Pzdtc) (5,10)]. All the newly synthesized compounds have been characterized by elemental analyses, molecular weight measurements and spectral (IR, 1H & 13C NMR and ESI mass) studies. Sodium salt of heterocyclic dithiocarbamates and their corresponding triphenyl antimony(V) bromo- and bis(dithiocarbamate) derivatives have also been screened for their antimicrobial activity against bacteria S. aureus (gram +ve), E. coli, Z. mobilies and P. aeruginosa (gram ve) and fungi ( P. chrysosprium, A. solani, P. chrysogenum and F. oxisporum ).

Keywords: triphenyl antimony(V) derivatives, heterocyclic dithiocarbamates, antimicrobial activity, spectral studies, anisobidante manner.

Country: India, Subject Area: Chemistry

Pages: 1601 - 1606

Edition: Volume 8 Issue 7, July 2019

How to Cite this Article?

Deepak Kumar Sharma, Jyoti Sharma, Ramavatar Sharma, "Syntheses, Characterization and Antimicrobial Activity of Triphenyl Antimony (V) Derivatives of Heterocyclic Dithiocarbamate", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive/v8i7/show_abstract.php?id=ART20199902, Volume 8 Issue 7, July 2019, 1601 - 1606

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