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Antiplasmodial and Toxicological Effects of Ethanolic Extracts of Moringaoleifera and Annonamuricata Leaves on Albino Rats

Okolie N.J.C., Akio Blessing

Abstract: Malaria is a disease caused by Plasmodia species. In a bid to address the health problems posed by malaria especially in tropical regions, plant based products are often being resorted to. This study was aimed at evaluating the anti-plasmodial and toxicological effects of Moringa oleifera and Annona muricata ethanolic leaf extracts in albino rats. In this study, the experimental animals were all (except for the normal control) inoculated with Plasmodium berghei infected erythrocytes and were treated with the plant extracts and reference drug (combisunate). The suppressive ability and Biochemical indices were carried out after five days of treatment. The results showed that there was reduction in the parasitemia level of the groups treated with Annona muricata relative to the untreated control which was significant at p

Keywords: Toxicological, antiplasmodial, Moringa oleifera, Annona muricata,Plasmodium berghei

Country: Nigeria, Subject Area: Medical Microbiology

Pages: 1772 - 1776

Edition: Volume 8 Issue 5, May 2019

How to Cite this Article?

Okolie N.J.C., Akio Blessing, "Antiplasmodial and Toxicological Effects of Ethanolic Extracts of Moringaoleifera and Annonamuricata Leaves on Albino Rats", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive/v8i5/show_abstract.php?id=ART20198255, Volume 8 Issue 5, May 2019, 1772 - 1776

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