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Effect of Ketamine Nebulization in Reduction of Incidence and Severity of Post?Operative Sore Throat-A Prospective Comparative Study

Dr. M. G. Rajinish Singhm .D, Dr. K. Ravindran, Dr. Edward Johnson, S. Kanthammal

Abstract: OBJECTIVE:The main objective of this study was to evaluate the role of nebulized ketamine for attenuation of Post operative sore throat(POST) in patients undergoing surgeries under GA with tracheal intubation.METHODS :After written informed consent, 40 patients of ASA PS I,II scheduled for surgery under general anaesthesia were enrolled in this study.Patients were randomized into two groups; Group saline(S) received saline nebulization 5.0 ml and group ketamine(K) received ketamine 50 mg(1.0 ml) with 4.0 ml of saline nebulization for 15 min.GA was induced 10 min after completion of nebulization .The POST and hemodynamic monitoring were done pre-nebulization, pre-induction, post-extubation, and at 2, 4, 6, 8, 12 and 24 h post-operatively. POST was graded on a four?point scale(0?3).RESULTS:The incidence of POST was more in saline group than in ketamine group (9/20 vs 3/20; 45% vs 15%) with P = 0.04.The use of ketamine nebulization attenuated POST at 0, 2 h ,4 h ,6h,8h,12h,24h post?operatively (P < 0.05).The severity of POST was more at 0,2,4,6,8 hr after surgery in saline group than ketamine group (p

Keywords: Ketamine nebulistion, Post Operative sore throat.

Country: India, Subject Area: Medical Science

Pages: 1413 - 1414

Edition: Volume 8 Issue 3, March 2019

How to Cite this Article?

Dr. M. G. Rajinish Singhm .D, Dr. K. Ravindran, Dr. Edward Johnson, S. Kanthammal, "Effect of Ketamine Nebulization in Reduction of Incidence and Severity of Post?Operative Sore Throat-A Prospective Comparative Study", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive/v8i3/show_abstract.php?id=ART20196322, Volume 8 Issue 3, March 2019, 1413 - 1414

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