Search for Articles:

Recently Downloaded: Paper ID: NOV151152, Total 392 Articles Downloaded Today





Antipsoriatic and Antieczematic Activity of Polyherbal Developed Gel on Swiss Albino Mice

Farah Khan, V. Nagulwar, S. Deshpande

Abstract: Psoriasis is distinguished by hyper-proliferation and unusual differentiation of epidermal keratinocytes, lymphocyte infiltration containing mainly of T lymphocytes. Psoriasis may be treated mainly by topical and dermal route because systemic therapy or phototherapy mainly concerns with the possible tissues toxicity and sometimes result in carcinogenicity. Beyond the various presently existing management options of psoriasis, topical therapy is the most widely used. Developed gel (4.5 % w/w Carbapol 934) Swiss albino mice give relevant result for treatment of psoriasis, without any tissue toxicity such as redness, erythematic in animal skin, as well as convulsion, tremor, circling, depression, hypothermia and mortality. Percent drug activity of Developed gel (4.5 % w/w Carbapol 934) was found to be 19.37 % which show a significant antipsoriatic effect in comparison of standard drug Derobin? (1.125 w/w) 12.90 %. Developed polyherbal gel is more effective as compared to standard drug Derobin?.

Keywords: Psoriasis, Derobin? (1.125 w/w), Developed gel (4.5 % w/w Carbapol 934)

Country: India, Subject Area: Histopathology

Pages: 348 - 350

Edition: Volume 8 Issue 2, February 2019

How to Cite this Article?

Farah Khan, V. Nagulwar, S. Deshpande, "Antipsoriatic and Antieczematic Activity of Polyherbal Developed Gel on Swiss Albino Mice", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive/v8i2/ART20194977.pdf, Volume 8 Issue 2, February 2019, 348 - 350

Download PDF


Viewed 33 times.

Downloaded 12 times.